(S) -Ebalzotan

(S) -Ebalzotan is the S-form of Ebalzotan. Ebalzotan is a 5-HT1A receptor agonist with activity in the study of depression. Ebalzotan can serve as a precursor to important active pharmaceutical ingredients. The synthesis of Ebalzotan involves a multi-enzyme catalyzed reduction reaction to obtain saturated primary or secondary alcohols in high yields and high enantioselectivity[1].

Product Specifications

CAS Number

294843-95-1

UNSPSC

12352005

Target

5-HT Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Neurological Disease

Smiles

CC(C)NC(C1=C2C(OC[C@H](C2)N(C(C)C)CCC)=CC=C1)=O

Molecular Formula

C19H30N2O2

Molecular Weight

318.45

References & Citations

[1]Elisabetta Brenna, et al. Synthesis of robalzotan, ebalzotan, and rotigotine precursors via the stereoselective multienzymatic cascade reduction of α, β-unsaturated aldehydes. J Org Chem. 2013 May 17;78 (10) :4811-22.