(S) -Ramosetron
(S) -Ramosetron ((S) -YM060 free base) is an orally active antagonist of the 5-hydroxytryptamine 5-HT3 receptor. (S) -Ramosetron is promising for research of diseases related to nausea and vomiting, irritable bowel syndrome (IBS) [1].
Product Specifications
CAS Number
132036-90-9
Product Name Alternative
(S) -YM060 (free base)
UNSPSC
12352005
Target
5-HT Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Smiles
O=C([C@@H]1CC2=C(N=CN2)CC1)C3=CN(C)C4=CC=CC=C34
Molecular Formula
C17H17N3O
Molecular Weight
279.34
References & Citations
[1]Ohta M, et al. Novel 5-hydroxytryptamine (5-HT3) receptor antagonists. III. Pharmacological evaluations and molecular modeling studies of optically active 4,5,6,7-tetrahydro-1H-benzimidazole derivatives. Chem Pharm Bull (Tokyo) . 1996 Sep;44 (9) :1707-16.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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