(S) -Ramosetron

(S) -Ramosetron ((S) -YM060 free base) is an orally active antagonist of the 5-hydroxytryptamine 5-HT3 receptor. (S) -Ramosetron is promising for research of diseases related to nausea and vomiting, irritable bowel syndrome (IBS) [1].

Product Specifications

CAS Number

[132036-90-9]

Product Name Alternative

(S) -YM060 (free base)

UNSPSC

12352005

Target

5-HT Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Smiles

O=C([C@@H]1CC2=C(N=CN2)CC1)C3=CN(C)C4=CC=CC=C34

Molecular Formula

C17H17N3O

Molecular Weight

279.34

References & Citations

[1]Ohta M, et al. Novel 5-hydroxytryptamine (5-HT3) receptor antagonists. III. Pharmacological evaluations and molecular modeling studies of optically active 4,5,6,7-tetrahydro-1H-benzimidazole derivatives. Chem Pharm Bull (Tokyo) . 1996 Sep;44 (9) :1707-16.