Oxomemazine (hydrochloride)
Oxomemazine hydrochloride is a phenothiazine-based histamine H1-receptor blocker with pronounced antimuscarinic properties. Oxomemazine hydrochloride is a selective antagonist for muscarinic M1 receptor, displays about 20-fold difference in the affinity for high (Ki= 84 nM, M1 receptor) and low (Ki= 1.65 μM, M2 receptor) affinity sites[1]. Oxomemazine hydrochloride an antihistamine and anticholinergic agent used for the study of cough treatment[2].
Product Specifications
CAS Number
4784-40-1
UNSPSC
12352005
Target
Histamine Receptor; mGluR
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
O=S1(C2=C(N(CC(CN(C)C)C)C3=C1C=CC=C3)C=CC=C2)=O.Cl
Molecular Formula
C18H23ClN2O2S
Molecular Weight
366.91
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MGluR1; mGluR2
Frequently Asked Questions
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