Ketoprofen (sodium)
Ketoprofen (RP-19583) sodium is a non-steroidal anti-inflammatory agent. Ketoprofen sodium can inhibit the activity of Cyclooxygenase with IC50 values of 2 nM (COX-1) and 26 nM (COX-2) . Ketoprofen is potential in the research of inflammation, immunology, and metabolic disease such as obesity[1][2][3].
Product Specifications
CAS Number
57495-14-4
Product Name Alternative
19583 RP-Na
UNSPSC
12352005
Target
COX
Related Pathways
Immunology/Inflammation
Field of Research
Cancer; Metabolic Disease; Inflammation/Immunology
Smiles
O=C(C(C)C1=CC(C(C2=CC=CC=C2)=O)=CC=C1)O[Na]
Molecular Formula
C16H13NaO3
Molecular Weight
276.26
References & Citations
[1]Palomer A, et al. Structure-based design of cyclooxygenase-2 selectivity into ketoprofen. Bioorg Med Chem Lett. 2002 Feb 25;12 (4) :533-7.|[2]NamHyeon Kang Ketoprofen alleviates diet-induced obesity and promotes white fat browning in mice via the activation of COX-2 through mTORC1-p38 signaling pathway. Pflugers Arch. 2020 May;472 (5) :583-596.|[3]Denisa Dan, et al. Ketoprofen affects the mammary immune response in dairy cows in vivo and in vitro. J Dairy Sci. 2018 Dec;101 (12) :11321-11329.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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