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Colupulone

Colupulone is a β-acid resin component found in hops (Humulus lupulus) and exhibits antibacterial and anti-larval activity against Culex mosquitoes. Colupulone can be used in studies related to infectious diseases[1][2][3].

Product Specifications

CAS Number

21621-94-3

UNSPSC

12352005

Target

Bacterial; Insecticide

Related Pathways

Anti-infection; Others

Field of Research

Infection

Smiles

O=C(C(C)C)C1=C(C(C/C=C(C)\C)=C(C(C/C=C(C)\C)(C/C=C(C)\C)C1=O)O)O

Molecular Formula

C25H36O4

Molecular Weight

400.55

References & Citations

[1]Connett B E, et al. Chemistry of hop constituents. Part XXXIV. Methylation of some hop resins[J]. Journal of the Chemical Society C: Organic, 1969 (2) : 340-344.|[2]Makri A, et al. Colupulone, colupone and novel deoxycohumulone geranyl analogues as larvicidal agents against Culex pipiens. Pest Manag Sci. 2022 Oct;78 (10) :4217-4222.|[3]Li Y, et al. Identification of colupulone and lupulone as the main contributors to the antibacterial activity of hop extracts using activity-guided fractionation and metabolome analysis. Food Res Int. 2023 Jul;169:112832.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Frequently Asked Questions

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