Seletalisib (Standard)

Seletalisib (Standard) is the analytical standard of Seletalisib. This product is intended for research and analytical applications. Seletalisib (UCB5857) is potent and selective PI3Kδ inhibitor with an IC50 of 12 nM.

Product Specifications

CAS Number

[1362850-20-1]

UNSPSC

12352100

Target

PI3K; Reference Standards

Related Pathways

Others; PI3K/Akt/mTOR

Field of Research

Inflammation/Immunology

Smiles

FC(F)(F)[C@H](NC1=C2C(C=CC=N2)=NC=N1)C3=CC4=CC=CC(Cl)=C4N=C3C5=CC=C[N+]([O-])=C5

Molecular Formula

C23H14ClF3N6O

Molecular Weight

482.85

References & Citations

[1]Allen RA, et al. Seletalisib: Characterization of a Novel, Potent, and Selective Inhibitor of PI3Kδ. J Pharmacol Exp Ther. 2017 Apr 25. pii: jpet.116.237347.