Gepotidacin (mesylate hydrate) (Standard)

Niacin (Standard) is the analytical standard of Niacin. This product is intended for research and analytical applications. Niacin (Vitamin B3) is an orally active water-soluble B3 vitamin that is an essential nutrient for humans. Niacin (Vitamin B3) plays a key role in energy metabolism, cell signaling cascades regulating gene expression and apoptosis. Niacin (Vitamin B3) is also used in the study of cardiovascular diseases[1][2].

Product Specifications

CAS Number

[1624306-20-2]

UNSPSC

12352005

Target

Antibiotic; Bacterial; Reference Standards; Topoisomerase

Related Pathways

Anti-infection; Cell Cycle/DNA Damage; Others

Field of Research

Infection

Smiles

O=C(C=NC(C=C1)=C23)N3[C@H](CN4CCC(NCC5=CC(CCCO6)=C6C=N5)CC4)CN2C1=O.CS(=O)(O)=O.O.O

Molecular Formula

C25H36N6O8S

Molecular Weight

580.65

References & Citations

[1]Gibson EG, et al. Mechanistic and Structural Basis for the Actions of the Antibacterial Gepotidacin against Staphylococcus aureus Gyrase. ACS Infect Dis. 2019 Apr 12;5 (4) :570-581. |[2]Watkins RR, et al. Gepotidacin: a novel, oral, 'first-in-class' triazaacenaphthylene antibiotic for the treatment of uncomplicated urinary tract infections and urogenital gonorrhoea. J Antimicrob Chemother. 2023 May 3;78 (5) :1137-1142.