Erlosiban
Erlosiban (OBE001) is an orally active non-peptide type oxytocin receptor antagonist. Erlosiban inhibits the increase of intracellular calcium concentration, thereby reducing uterine smooth muscle contraction. Erlosiban can be used for research on premature birth and to improve embryo implantation and pregnancy rate in assisted reproductive technology (AR) .
Product Specifications
CAS Number
[1477482-19-1]
Product Name Alternative
OBE001
UNSPSC
12352005
Target
Oxytocin Receptor
Related Pathways
GPCR/G Protein
Field of Research
Endocrinology
Smiles
O=C(N1C/C(C[C@H]1CO)=N\OC)C2=CC=C(C3=CC=CC=C3C)C=C2
Molecular Formula
C20H22N2O3
Molecular Weight
338.40
References & Citations
[1]Pohl O, et al. Effects of the Oral Oxytocin Receptor Antagonist Tocolytic OBE001 on Reproduction in Rats. Reprod Sci. 2016 Apr;23 (4) :439-47. |[2]Pohl O, et al. Pharmacokinetic interactions of OBE001 and betamethasone in healthy female volunteers. J Clin Pharm Ther. 2015 Jun;40 (3) :328-32.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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