Neceprevir
Neceprevir (ACH-2684) is a HCV NS3 protease inhibitor. Neceprevir has potent antiviral activities against different genotypes and against known resistant variants (such as R155, Al56 and D168) by the formation a highly stable complex with NS3 prolease. Neceprevir can be used for Hepatitis C virus infection research[1].
Product Specifications
CAS Number
[1229626-28-1]
Product Name Alternative
ACH-2684; Deldeprevir
UNSPSC
12352005
Target
HCV Protease
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Field of Research
Infection
Smiles
O=C([C@]([C@]1([H])/C=C\CCCCC[C@@H]2CC(N3CC(F)(F)CCC3)=O)(C1)NC([C@@](C[C@@H](OC4=CC(C5=NC(C(C)C)=CS5)=NC6=C(C)C(OC)=CC=C46)C7)([H])N7C2=O)=O)NS(=O)(C8CC8)=O
Molecular Formula
C45H56F2N6O8S2
Molecular Weight
911.09
References & Citations
[1]Yang X, et al. INHIBITION OF HCV USING AAV VECTORS TO DELIVER ARTIFICIAL ANTI-HCV MIRNAS: 1860[J]. Hepatology, 2010, 52: 1204A.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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