Indoximod (Standard)

Indoximod (Standard) is the analytical standard of Indoximod. This product is intended for research and analytical applications. Indoximod (1-Methyl-D-tryptophan) is an orally active indoleamine 2,3-dioxygenase (IDO) pathway inhibitor. Indoximod acts as a Trp mimetic in regulating mTOR. Indoximod is an immunometabolic adjuvant used for the research of cancer[1][2].

Product Specifications

CAS Number

[110117-83-4]

UNSPSC

12352100

Target

Indoleamine 2,3-Dioxygenase (IDO) ; Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Cancer

Smiles

N[C@H](CC1=CN(C)C2=CC=CC=C12)C(O)=O

Molecular Formula

C12H14N2O2

Molecular Weight

218.26

References & Citations

[1]Hou DY, et al. Inhibition of indoleamine 2,3-dioxygenase in dendritic cells by stereoisomers of 1-methyl-tryptophancorrelates with antitumor responses. Cancer Res. 2007 Jan 15;67 (2) :792-801.|[2]Metz R, et al. IDO inhibits a tryptophan sufficiency signal that stimulates mTOR: A novel IDO effector pathway targeted by D-1-methyl-tryptophan. Oncoimmunology. 2012;1 (9) :1460-1468.