2ccPA
2ccPA is a Cyclic phosphatidic acid derivative. 2ccPA decreases ECM expression, increases the intracellular cAMP levels. 2ccPA decreases the protein expression levels of type I collagen, CCN2 and αSMA. 2ccPA has inhibitory effects on the progression of skin fibrosis by abrogating ECM production from activated skin fibroblasts[1].
Product Specifications
CAS Number
[633278-53-2]
UNSPSC
12352211
Target
Collagen
Related Pathways
Cytoskeleton
Field of Research
Others
Smiles
CCCCCCCC/C=C\CCCCCCCC(OCC1COP(O)(C1)=O)=O
Molecular Formula
C22H41O5P
Molecular Weight
416.53
References & Citations
[1]Higuchi T, et al. Antifibrotic effects of 2-carba cyclic phosphatidic acid (2ccPA) in systemic sclerosis: contribution to the novel treatment. Arthritis Res Ther. 2019 Apr 18;21 (1) :103.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Collagen I
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