PNA5
PNA5 is a novel, blood-brain barrier permeable glycosylated angiotensin- (1-7) peptide and MasR agonist. PNA5 inhibits IL-7, increases IL-10. PNA5 inhibits ROS generation, decreases Iba-1 expression. PNA5 exhibits sustained cognitive protective effects. PNA5 rescues blunted cerebral functional hyperemia. PNA5 can be used in the research of inflammation-related brain diseases[1].
Product Specifications
CAS Number
[2186644-51-7]
UNSPSC
12352005
Target
Interleukin Related; Reactive Oxygen Species (ROS)
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Field of Research
Neurological Disease; Inflammation/Immunology; Cardiovascular Disease
Smiles
Molecular Formula
C45H71N13O16
Molecular Weight
1050.12
References & Citations
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-167153/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IL-10; IL-7
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