CID 16020046 (Standard)

CID 16020046 (Standard) is the analytical standard of CID 16020046. This product is intended for research and analytical applications. CID 16020046 is a potent and selective GPR55 antagonist and inhibits GPR55 constitutive activity with an IC50 of 0.15 μM. CID 16020046 inhibits GPR55-mediated Ca2+ signaling and GPR55-mediated ERK1/2 phosphorylation. CID 16020046 reduces wound healing in endothelial cells and is involved in the regulation of platelet function[1].

Product Specifications

CAS Number

[834903-43-4]

UNSPSC

12352100

Target

GPR55; Reference Standards

Related Pathways

GPCR/G Protein; Neuronal Signaling; Others

Field of Research

Cancer

Smiles

O=C(O)C1=CC=C(N(C2C3=CC=CC(O)=C3)C(C4=C2C(C5=CC=C(C)C=C5)=NN4)=O)C=C1

Molecular Formula

C25H19N3O4

Molecular Weight

425.44

References & Citations

[1]Kargl J, et al. A selective antagonist reveals a potential role of G protein-coupled receptor 55 in platelet and endothelial cell function. J Pharmacol Exp Ther. 2013 Jul;346 (1) :54-66.