Eltoprazine (hydrochloride) (Standard)

Eltoprazine (hydrochloride) (Standard) is the analytical standard of Eltoprazine (hydrochloride) . This product is intended for research and analytical applications. Eltoprazine (DU 28853) hydrochloride is a 5-HT1A/5-HT1B receptors agonist and a 5-HT2C receptor antagonist. Eltoprazine hydrochloride shows antiaggressive and anxiogenic effects[1][2].

Product Specifications

CAS Number

[98206-09-8]

UNSPSC

12352100

Target

5-HT Receptor; Reference Standards

Related Pathways

GPCR/G Protein; Neuronal Signaling; Others

Field of Research

Neurological Disease

Smiles

[H]Cl.N1(C2=C3OCCOC3=CC=C2)CCNCC1

Molecular Formula

C12H17ClN2O2

Molecular Weight

256.73

References & Citations

[1]Sijbesma H, et al. Eltoprazine, a drug which reduces aggressive behaviour, binds selectively to 5-HT1 receptor sites in the rat brain: an autoradiographic study. Eur J Pharmacol. 1990 Feb 20;177 (1-2) :55-66.|[2]Rocha B, et al. Chronic mianserin or eltoprazine treatment in rats: effects on the elevated plus-maze test and on limbic 5-HT2C receptor levels. Eur J Pharmacol. 1994 Sep 1;262 (1-2) :125-31.