Tyrphostin A1 (Standard)
Tyrphostin A1 (Standard) is the analytical standard of Tyrphostin A1. This product is intended for research and analytical applications. Tyrphostin A1 (AG9) can inhibit CD40L-stimulated IL-12 production and antigen-induced Th1 cell production in macrophage culture.
Product Specifications
CAS Number
2826-26-8
UNSPSC
12352100
Target
Interleukin Related; Reference Standards
Related Pathways
Immunology/Inflammation; Others
Field of Research
Inflammation/Immunology
Smiles
N#C/C(C#N)=C\C1=CC=C(OC)C=C1
Molecular Formula
C11H8N2O
Molecular Weight
184.19
References & Citations
[1]Du C, et al. Inhibition of CD40 signaling pathway by tyrphostin A1 reduces secretion of IL-12 in macrophage, Th1 cell development and experimental allergic encephalomyelitis in SJL/J mice. J Neuroimmunol. 2001 Mar 1;114 (1-2) :69-79.|[2]Ogura T, et al. Activation of background membrane conductance by the tyrosine kinase inhibitor tyrphostin A23 and its inactive analog tyrphostin A1 in guinea pig ventricular myocytes. Jpn J Pharmacol. 2001 Nov;87 (3) :235-9.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
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