Ketoconazole carbonyl-13C
Ketoconazole carbonyl-13C (Ketoconazol-13C) is 13C labeled Ketoconazole. Ketoconazole (R-41400) is an imidazole anti-fungal agent, a CYP3A4 and CYP24A1 inhibitor.
Product Specifications
Product Name Alternative
Ketoconazol-13C; R 41400-13C
UNSPSC
12352005
Target
Bacterial; Cytochrome P450; Fungal; Isotope-Labeled Compounds; Ras
Related Pathways
Anti-infection; GPCR/G Protein; MAPK/ERK Pathway; Metabolic Enzyme/Protease; Others
Applications
COVID-19-immunoregulation
Field of Research
Infection; Cancer
Smiles
O=[13C](C)N(CC1)CCN1C(C=C2)=CC=C2OC[C@H](O3)CO[C@]3(CN4C=CN=C4)C5=C(Cl)C=C(Cl)C=C5
Molecular Formula
C25 13CH28Cl2N4O4
Molecular Weight
532.42
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Seif El-Din SH, et al. Effect of ketoconazole, a cytochrome P450 inhibitor, on the efficacy of quinine and halofantrine against Schistosoma mansoni in mice. Korean J Parasitol. 2013 Apr;51 (2) :165-75.|[3]Eil C. Ketoconazole binds to the human androgen receptor. Horm Metab Res. 1992 Aug;24 (8) :367-70.|[4]Muindi JR et al. CYP24A1 inhibition enhances the antitumor activity of calcitriol. Endocrinology. 2010 Sep;151 (9) :4301-12.|[5]Amrita Datta, et al. High-throughput screening identified selective inhibitors of exosome biogenesis and secretion: A drug repurposing strategy for advanced cancer. Sci Rep. 2018 May 25;8 (1) :8161.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC700391-100 1x 100 µL
CD81 / TAPA-1 (1.3.3.22), CF770 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC470257-500 1x 500 µL
Cytokeratin, HMW (AE-3), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC940806-500 1x 500 µL
TYRP1 (Tyrosinase Related Protein 1) (TA99), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC680177-500 1x 500 µL
CD50 (ICAM-3) (101-1D2), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC740689-500 1x 500 µL
Cytokeratin 8 (K8.8), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details