(S) -LY-41
(S) -LY-41, R-enantiomer of LY-41 (HY-165624), is 2-Sminotetralin (HY-W022362) derivative and 8-OH-DPAT (HY-112061) analogue. (S) -LY-41 is a potent and selective 5-HT1A receptor agonist. (S) -LY-41 can reduce the accumulation of 5-hydroxytryptophan (the precursor for 5-HT synthesis) in the rat brain induced by decarboxylase inhibitors (NSD 1015) . (S) -LY-41 can lower the body temperature of rats and inhibit the escape response from the cage. (S) -LY-41 can induce the 5-HT behavioral syndrome. (S) -LY-41can be used for the research of neurological disease, such as depression and anxiety[1].
Product Specifications
UNSPSC
12352005
Target
5-HT Receptor; Drug Derivative; Drug Isomer
Related Pathways
GPCR/G Protein; Neuronal Signaling; Others
Field of Research
Neurological Disease
Smiles
CC(C1=CC=CC2=C1C[C@@H](N(CCC)CCC)CC2)=O
Molecular Formula
C18H27NO
Molecular Weight
273.41
References & Citations
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-165624A/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT1 Receptor
CAS Number
[136296-40-7]
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