AJ-3941

AJ-3941 is an orally active cerebrovascular-selective Calcium Channel antagonist having anti-lipid peroxidative action. AJ-3941 can ameliorate the brain infarction and edema after permanent focal cerebral ischemia[1][2].

Product Specifications

CAS Number

[143110-70-7]

UNSPSC

12352005

Target

Calcium Channel

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease; Cardiovascular Disease

Smiles

OC(/C=C\C(O)=O)=O.FC1=CC=C(C(N2CCN(CC2)C/C=C/C3=CC=CC=C3)C4=CC=CC=C4CO5)C5=C1.OC(/C=C\C(O)=O)=O

Molecular Formula

C35H35FN2O9

Molecular Weight

646.66

References & Citations

[1]Minato H, et al. Prevention by the new Ca2+ channel antagonist, AJ-3941, of loss of endothelium-dependent relaxation after subarachnoid hemorrhage in rats. Eur J Pharmacol. 1996 Nov 21;315 (3) :297-303.