MMV665917
MMV665917 is an orally active piperazine derivative with anti-Cryptosporidium parvum activity with an EC90 of 15 μM. MMV665917 significantly reduces the parasite load in a porcine model infected with C. hominis, decreases ovarian excretion, alleviates diarrhea symptoms and reduces intestinal mucosal damage. MMV665917 can be used for research on Cryptosporidium parvum disease[1].
Product Specifications
CAS Number
904576-65-4
UNSPSC
12352005
Target
Parasite
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O=C(NC1=CC=C(C([H])=C1)Cl)N2CCN(CC2)C3=NN4C(C=C3)=NN=C4
Molecular Formula
C16H16ClN7O
Molecular Weight
357.80
References & Citations
[1]Lee S, et al. Piperazine-Derivative MMV665917: An Effective Drug in the Diarrheic Piglet Model of Cryptosporidium hominis. J Infect Dis. 2019 Jun 19;220 (2) :285-293.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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