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SRI-29132

SRI-29132 is a potent leucine-rich repeat kinase 2 (LRRK2) inhibitor. SRI-29132 is promising for research of Parkinson’s disease[1].

Product Specifications

CAS Number

[1482305-44-1]

UNSPSC

12352005

Target

LRRK2

Related Pathways

Autophagy

Field of Research

Neurological Disease

Smiles

O=C(C(CC)SC1=NN2C(C=C1)=NN=C2C3=CC=CS3)N4CCCCC4

Molecular Formula

C18H21N5OS2

Molecular Weight

387.52

References & Citations

[1]Moukha-Chafiq O, et al. Discovery of a Chiral 2,4-Substituted Pyrrolo[2,3-d]pyrimidine as a Potent, Selective, and Orally Bioavailable LRRK2 Inhibitor. J Med Chem. 2025 May 22;68 (10) :9926-9946.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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