KAT-IN-2

KAT-IN-2 (7) is a potent and selective kynurenine aminotransferase II (KATII) inhibitor[1][2].

Product Specifications

CAS Number

164789-02-0

UNSPSC

12352005

Target

Histone Methyltransferase

Related Pathways

Epigenetics

Field of Research

Others

Smiles

O=C(C(CC(C1=CC(Cl)=CC=C1N)=O)N)O

Molecular Formula

C10H11ClN2O3

Molecular Weight

242.66

References & Citations

[1]Roberto Pellicciari, et al. Modulators of the kynurenine pathway of tryptophan metabolism: synthesis and preliminary biological evaluation of (S) -4- (ethylsulfonyl) benzoylalanine, a potent and selective kynurenine aminotransferase II (KAT II) inhibitor. ChemMedChem. 2006 May;1 (5) :528-31.|[2]M Varasi, et al. Derivatives of kynurenine as inhibitors of rat brain kynurenine aminotransferase. European Journal of Medicinal Chemistry. Volume 31, Issue 1, 1996, Pages 11-21.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported