HB-230
HB-230 is a red fluorescent transglutaminase 2 (TG2) probe. HB-230 complexes with TG2 and α2-macroglobulin via the LRP1 pathway for efficient endocytosis. The excitation and emission wavelengths of HB-230 are 649 and 665 nm, respectively[1].
Product Specifications
CAS Number
3031522-14-9
UNSPSC
12352005
Target
Fluorescent Dye; Glutaminase
Related Pathways
Metabolic Enzyme/Protease; Others
Smiles
O=C(N1[C@@H](CCC1)C(N[C@H](C(N)=O)CC2=CC=CC=C2)=O)[C@@H](NC([C@H](CC/C=C/C(N(C)C)=O)NC([C@H]3N(CCC3)C(C)=O)=O)=O)CCNC(CCCCC[N+]4=C(/C=C/C=C/C=C5C(C)(C6=CC(S(=O)(O)=O)=CC=C6N\5C)C)C(C)(C)C7=CC(S(=O)([O-])=O)=CC=C47)=O
Molecular Formula
C66H86N10O14S2
Molecular Weight
1307.58
References & Citations
[1]Chaitan Khosla, et al. Compositions and methods for transglutaminase-mediated endocytosis. WO2024049543A1. USA. 2024-03-07.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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