BMS-791826

BMS-791826 is a selective glucocorticoid receptor modulator. BMS-791826 effectively binds to glucocorticoid receptors and effectively inhibits AP-1 and NF-κB-dependent reporter. BMS-791826 can be used in the research of inflammatory diseases[1].

Product Specifications

CAS Number

[1008116-73-1]

UNSPSC

12352005

Target

AP-1; Glucocorticoid Receptor; NF-κB

Related Pathways

Immunology/Inflammation; NF-κB; Vitamin D Related/Nuclear Receptor

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Smiles

O=C(NC1=NN=CS1)C(C)([C@@H]2C3=CC=C(C4=CC(F)=C(C=C4)C(N(C)CC)=O)N=C3OC5=CC=CC=C52)C

Molecular Formula

C28H26FN5O3S

Molecular Weight

531.60

References & Citations

[1]Hu Y, et al. Development of a Molecular Signature to Monitor Pharmacodynamic Responses Mediated by In Vivo Administration of Glucocorticoids. Arthritis Rheumatol. 2018 Aug;70 (8) :1331-1342.