BMS-791826
BMS-791826 is a selective glucocorticoid receptor modulator. BMS-791826 effectively binds to glucocorticoid receptors and effectively inhibits AP-1 and NF-κB-dependent reporter. BMS-791826 can be used in the research of inflammatory diseases[1].
Product Specifications
CAS Number
[1008116-73-1]
UNSPSC
12352005
Target
AP-1; Glucocorticoid Receptor; NF-κB
Related Pathways
Immunology/Inflammation; NF-κB; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Smiles
O=C(NC1=NN=CS1)C(C)([C@@H]2C3=CC=C(C4=CC(F)=C(C=C4)C(N(C)CC)=O)N=C3OC5=CC=CC=C52)C
Molecular Formula
C28H26FN5O3S
Molecular Weight
531.60
References & Citations
[1]Hu Y, et al. Development of a Molecular Signature to Monitor Pharmacodynamic Responses Mediated by In Vivo Administration of Glucocorticoids. Arthritis Rheumatol. 2018 Aug;70 (8) :1331-1342.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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