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AK-135 (hydrochloride)

AK-135 hydrochloride is a Menadione (HY-B0332) derivative. AK-135 hydrochloride restores the electron flow in defective respiratory chain systems. AK-135 hydrochloride decreases LDH release, increases the amount of ATP. AK-135 hydrochloride has a protective effect against myocardial injury[1].

Product Specifications

CAS Number

[75397-64-7]

UNSPSC

12352005

Target

ATP Synthase; Drug Derivative; Lactate Dehydrogenase

Related Pathways

Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Others

Field of Research

Cardiovascular Disease

Smiles

O=C1C2=C(C(C(CN3CCCCC3)=C1C)=O)C=CC=C2.Cl

Molecular Formula

C17H20ClNO2

Molecular Weight

305.80

References & Citations

[1]Shneyvays V, et al. Effects of menadione and its derivative on cultured cardiomyocytes with mitochondrial disorders. J Mol Cell Cardiol. 2005 Jul;39 (1) :149-58.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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