SCR1693
SCR1693 is a selective, reversible, orally active and noncompetitive inhibitor of AChE (IC50 = 0.68 μM) as well as a calcium channel blocker. SCR1693 reduces tau phosphorylation levels, and inhibits the generation and release of Aβ. SCR1693 restores insulin signaling and improves cognitive deficits. SCR1693 can be used for the study of Alzheimer's disease, especially which complicated with type 2 diabetes mellitus[1][2][3].
Product Specifications
CAS Number
1442559-20-7
UNSPSC
12352005
Target
Akt; Amyloid-β; Calcium Channel; Cholinesterase (ChE) ; GSK-3; Phosphatase; PKA; Tau Protein
Related Pathways
Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; PI3K/Akt/mTOR; Stem Cell/Wnt; TGF-beta/Smad
Applications
Neuroscience-Neurodegeneration
Field of Research
Metabolic Disease; Neurological Disease
Smiles
O=C(C1=C(C)N=C2NC3=C(CC(C)(CC3)C)C(N)=C2C1C4=C(Cl)C=CC=C4)OCC
Molecular Formula
C24H28ClN3O2
Molecular Weight
425.95
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE
Frequently Asked Questions
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