Lysyl-phenylalanyl-lysine

Lysyl-phenylalanyl-lysine (Compound KFK) is a tripeptide and belongs to the peptide segments related to thrombospondin-1 (TSP-1) (HY-P0299) . Lysyl-phenylalanyl-lysine can activate LAP-TGF-β1 and release active TGF-β1, thereby inhibiting abnormal expression of MMP. Lysyl-phenylalanyl-lysine can be used for research on skin aging-related diseases and poor wound healing[1].

Product Specifications

CAS Number

[54925-87-0]

UNSPSC

12352005

Target

MMP; TGF-β Receptor

Related Pathways

Metabolic Enzyme/Protease; TGF-beta/Smad

Field of Research

Others

Smiles

NCCCC[C@@H](C(O)=O)NC([C@@H](NC([C@@H](N)CCCCN)=O)CC1=CC=CC=C1)=O

Molecular Formula

C21H35N5O4

Molecular Weight

421.53

References & Citations

[1]Cauchard JH, et al. Activation of latent transforming growth factor beta 1 and inhibition of matrix metalloprotease activity by a thrombospondin-like tripeptide linked to elaidic acid. Biochem Pharmacol. 2004 Jun 1;67 (11) :2013-22.