AGN-190383
AGN-190383 is a bee venom phospholipase A2 inhibitor. AGN 190383 inhibits both hormone-operated and depolarization-dependent calcium mobilization as well as fMLP stimulated increases in free cytosolic calcium. AGN-190383 has anti-inflammatory activity[1].
Product Specifications
CAS Number
[120755-15-9]
UNSPSC
12352005
Target
Phospholipase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology
Smiles
O=C1OC(C(C(CCCCCCCCCCCC)OC(C)=O)=C1)O
Molecular Formula
C19H32O5
Molecular Weight
340.45
References & Citations
[1]De Vries GW, et al. AGN 190383, a novel phospholipase inhibitor with topical anti-inflammatory activity. Agents Actions. 1991 Sep;34 (1-2) :70-2.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Phospholipase A
Curated Selection
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