VAL-083 (Standard)
VAL-083 (Standard) is the analytical standard of VAL-083. This product is intended for research and analytical applications. VAL-083 is an alkylating agent that creates N7 methylation on DNA, with antitumor activity.
Product Specifications
CAS Number
[23261-20-3]
UNSPSC
12352100
Target
DNA Alkylator/Crosslinker; Reference Standards
Related Pathways
Cell Cycle/DNA Damage; Others
Field of Research
Cancer
Smiles
O[C@H]([C@H](O)[C@]1(OC1)[H])[C@@]2([H])CO2
Molecular Formula
C6H10O4
Molecular Weight
146.14
References & Citations
[1]Kaiji Hu, et al. Abstract 811: VAL083, a novel N7 alkylating agent, surpasses NSC 362856 activity and inhibits cancer stem cells providing a new potential treatment option for glioblastoma multiforme. Cancer Research. 2012 Mar 31-Apr 4.|[2]Jiang X, et al. Dianhydrogalactitol, a potential multitarget agent, inhibits glioblastoma migration, invasion, and angiogenesis. Biomed Pharmacother. 2017 Jul;91:1065-1074.|[3]Peng C, et al. 1,2:5,6-dianhydrogalactitol inhibits human glioma cell growth in vivo and in vitro by arresting the cell cycle at G2/M phase. Acta Pharmacol Sin. 2017 Apr;38 (4) :561-570.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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