Upamostat hydrogen (sulfate)
Upamostat (WX-671) hydrogen sulfate, a prodrug of WX-UK1 , is an orally active serine protease inhibitor. Upamostat hydrogen sulfate inhibits the urokinase-type plasminogen activator (uPA) system, blocking the plasminogen activation process mediated by it, thereby suppressing the invasion, migration and metastasis of tumor cells. Upamostat hydrogen sulfate can be used in the research of metastatic breast cancer and locally advanced pancreatic cancer[1].
Product Specifications
CAS Number
798560-68-6
Product Name Alternative
WX-671 hydrogen (sulfate)
UNSPSC
12352005
Target
PAI-1; Ser/Thr Protease
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Smiles
O=C(N1CCN(C([C@@H](NS(=O)(C2=C(C(C)C)C=C(C(C)C)C=C2C(C)C)=O)CC3=CC=CC(C(NO)=N)=C3)=O)CC1)OCC.O=C(N4CCN(C([C@@H](NS(=O)(C5=C(C(C)C)C=C(C(C)C)C=C5C(C)C)=O)CC6=CC=CC(C(NO)=N)=C6)=O)CC4)OCC.O=S(O)(O)=O
Molecular Formula
C64H96N10O16S3
Molecular Weight
1357.70
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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