Temoporfin (Standard)

Temoporfin (Standard) is the analytical standard of Temoporfin. This product is intended for research and analytical applications. Temoporfin (m-THPC), a reduced porphyrin, is a potent second-generation photosensitizer. Temoporfin can be used in the research of photodynamic therapy (PDT) for head and neck cancers[1][2][3].

Product Specifications

CAS Number

[122341-38-2]

UNSPSC

12352100

Target

Reactive Oxygen Species (ROS) ; Reference Standards

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others

Field of Research

Cancer

Smiles

OC1=CC=CC(/C2=C3CCC(/C(C4=CC(O)=CC=C4)=C5C=C/C(N/5)=C(C6=CC(O)=CC=C6)/C(C=C/7)=NC7=C(C8=CC(O)=CC=C8)/C9=CC=C2N9)=N\3)=C1

Molecular Formula

C44H32N4O4

Molecular Weight

680.75

References & Citations

[1]Senge MO, et, al. Temoporfin (Foscan®, 5,10,15,20-tetra (m-hydroxyphenyl) chlorin) --a second-generation photosensitizer. Photochem Photobiol. 2011 Nov-Dec;87 (6) :1240-96.|[2]Rovers JP, et, al. Effective treatment of liver metastases with photodynamic therapy, using the second-generation photosensitizer meta-tetra (hydroxyphenyl) chlorin (mTHPC), in a rat model. Br J Cancer. 1999 Oct;81 (4) :600-8. |[3]Reshetov V, et, al. Photodynamic therapy with conventional and PEGylated liposomal formulations of mTHPC (temoporfin) : comparison of treatment efficacy and distribution characteristics in vivo. Int J Nanomedicine. 2013;8:3817-31.