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ABC47

ABC47 is a potent inhibitor of serine hydrolases. ABC47 shows IC50s of 0.03 and 0.1 μM for ABHD4 and ABHD3, respectively. ABC47 plays an important role in infantile neuronal ceroid lipofuscinosis research[1].

Product Specifications

CAS Number

1831135-57-9

UNSPSC

12352005

Target

Phospholipase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Metabolic Disease

Purity

99.80

Smiles

O=C(N1CCC(CC1)C2=CC=CC=C2)ON3C(N4CCN(CC4C3=O)CC5=CC=C(C=C5)OC6=CC=CC=C6)=O

Molecular Formula

C31H32N4O5

Molecular Weight

540.61

References & Citations

[1]Armand B Cognetta 3rd, et al. Selective N-Hydroxyhydantoin Carbamate Inhibitors of Mammalian Serine Hydrolases. Chem Biol. 2015 Jul 23;22 (7) :928-37. doi: 10.1016/j.chembiol.2015.05.018

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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