Estrogen receptor modulator 11
Estrogen receptor modulator 11 (Compound 27) is a tetrahydroisoquinoline derivative. Estrogen receptor modulator 11 has a certain affinity for estrogen receptors (ER), with IC50 values of 285 nM and 421 nM for ERα and ERβ, respectively. Estrogen receptor modulator 11 lacks antagonist activity in the MCF-7 cellular assay[1].
Product Specifications
CAS Number
[96719-63-0]
UNSPSC
12352005
Target
Estrogen Receptor/ERR
Related Pathways
Vitamin D Related/Nuclear Receptor
Field of Research
Others
Smiles
FC1=CC=C(C2C3=CC=C(C=C3CCN2C4=CC=CC=C4)O)C=C1
Molecular Formula
C21H18FNO
Molecular Weight
319.37
References & Citations
[1]Renaud J, et al. Estrogen receptor modulators: identification and structure-activity relationships of potent ERalpha-selective tetrahydroisoquinoline ligands. J Med Chem. 2003 Jul 3;46 (14) :2945-57.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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