MMV019662
MMV019662 is a PfNCR1 inhibitor. MMV019662 specifically interact with PfNCR1. MMV019662 induces opening of the SSD. MMV019662 can be used in the research of Plasmodium falciparum infection[1][2].
Product Specifications
CAS Number
[896349-19-2]
UNSPSC
12352005
Target
Parasite
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O=C(NCC(C1=CC=C2OCOC2=C1)N3CCN(C4=CC=C(OC)C=C4)CC3)C5CCCCC5
Molecular Formula
C27H35N3O4
Molecular Weight
465.59
References & Citations
[1]Kohling A, et al. Targeting ligand binding sites in Plasmodium falciparum NCR1 enables antimalarial drug discovery. bioRxiv, 2025: 2025.11. 11.687791.|[2]Zhang Z, et al. The Plasmodium falciparum NCR1 membrane protein is a novel antimalarial target that exports cholesterol to maintain membrane homeostasis. bioRxiv, 2024: 2024.09. 30.615907.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Plasmodium
Curated Selection
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