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MMV019662

MMV019662 is a PfNCR1 inhibitor. MMV019662 specifically interact with PfNCR1. MMV019662 induces opening of the SSD. MMV019662 can be used in the research of Plasmodium falciparum infection[1][2].

Product Specifications

CAS Number

896349-19-2

UNSPSC

12352005

Target

Parasite

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

O=C(NCC(C1=CC=C2OCOC2=C1)N3CCN(C4=CC=C(OC)C=C4)CC3)C5CCCCC5

Molecular Formula

C27H35N3O4

Molecular Weight

465.59

References & Citations

[1]Kohling A, et al. Targeting ligand binding sites in Plasmodium falciparum NCR1 enables antimalarial drug discovery. bioRxiv, 2025: 2025.11. 11.687791.|[2]Zhang Z, et al. The Plasmodium falciparum NCR1 membrane protein is a novel antimalarial target that exports cholesterol to maintain membrane homeostasis. bioRxiv, 2024: 2024.09. 30.615907.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Plasmodium

Frequently Asked Questions

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