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NRMA-I

NRMA-I is the amide produrg of the small molecule nuclear receptor modulator. NRMA-I exhibits a higher exposure in the brain, indicating that a good blood-brain barrier (BBB) penetration. NRMA-I can be used for research of central nervous system diseases related to nuclear receptors, such as Alzheimer's disease and Parkinson's disease[1].

Product Specifications

CAS Number

[1417653-47-4]

UNSPSC

12352101

Target

Drug Intermediate

Related Pathways

Others

Field of Research

Neurological Disease

Smiles

O=C(CC1=CC(I)=C(C(I)=C1)OC2=CC=C(C(I)=C2)O)NC

Molecular Formula

C15H12I3NO3

Molecular Weight

634.97

References & Citations

[1]Scanlan TS, et al., Amide prodrugs of small molecule nuclear receptor modulators. WO2019168842

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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