NRMA-9

NRMA-9 is the amide produrg of the small molecule nuclear receptor modulator. NRMA-9 exhibits a higher exposure in the brain, indicating that a good blood-brain barrier (BBB) penetration. NRMA-9 can be used for research of central nervous system diseases related to nuclear receptors, such as Alzheimer's disease and Parkinson's disease[1].

Product Specifications

CAS Number

[2375659-16-6]

UNSPSC

12352005

Target

Drug Intermediate

Related Pathways

Others

Field of Research

Neurological Disease

Smiles

O=C(CC1=CC=C(C(Cl)=C1)SCCCOC2=C(CCC)C(ON=C3C(F)(F)F)=C3C=C2)NC

Molecular Formula

C23H24ClF3N2O3S

Molecular Weight

500.96

References & Citations

[1]Scanlan TS, et al., Amide prodrugs of small molecule nuclear receptor modulators. WO2019168842

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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