Anticancer agent 252
Anticancer agent 252 (compound 1) is a benzamide compound with selective anti-cancer activity against small cell lung cancer (SCLC) cells. Anticancer agent 252 inhibits murine SCLC (mSCLC) cell lines with an average EC50 of 3.21 μM. Anticancer agent 252 also inhibits human SCLC cell lines, H889, H2107, and H128[1].
Product Specifications
CAS Number
314284-36-1
UNSPSC
12352005
Target
Others
Related Pathways
Others
Field of Research
Cancer
Smiles
O=C(C1=CC=C(Cl)C([N+]([O-])=O)=C1)N2CCN(C3=CC=CC=C3)CC2
Molecular Formula
C17H16ClN3O3
Molecular Weight
345.78
References & Citations
[1]Povedano JM, et al. A Multipronged Approach Establishes Covalent Modification of β-Tubulin as the Mode of Action of Benzamide Anti-cancer Toxins. J Med Chem. 2020 Nov 25;63 (22) :14054-14066.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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