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Anticancer agent 252

Anticancer agent 252 (compound 1) is a benzamide compound with selective anti-cancer activity against small cell lung cancer (SCLC) cells. Anticancer agent 252 inhibits murine SCLC (mSCLC) cell lines with an average EC50 of 3.21 μM. Anticancer agent 252 also inhibits human SCLC cell lines, H889, H2107, and H128[1].

Product Specifications

CAS Number

314284-36-1

UNSPSC

12352005

Target

Others

Related Pathways

Others

Field of Research

Cancer

Smiles

O=C(C1=CC=C(Cl)C([N+]([O-])=O)=C1)N2CCN(C3=CC=CC=C3)CC2

Molecular Formula

C17H16ClN3O3

Molecular Weight

345.78

References & Citations

[1]Povedano JM, et al. A Multipronged Approach Establishes Covalent Modification of β-Tubulin as the Mode of Action of Benzamide Anti-cancer Toxins. J Med Chem. 2020 Nov 25;63 (22) :14054-14066.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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