Glasdegib (Standard)
Glasdegib (Standard) is the analytical standard of Glasdegib. This product is intended for research and analytical applications. Glasdegib (PF-04449913) is a potent and orally bioavailable smoothened inhibitor. Glasdegib (PF-04449913) binds to human SMO (amino acids 181-787) with an IC50 of 4 nM[1].
Product Specifications
CAS Number
[1095173-27-5]
UNSPSC
12352100
Target
Reference Standards; Smo
Related Pathways
Others; Stem Cell/Wnt
Field of Research
Cancer
Smiles
O=C(NC1=CC=C(C#N)C=C1)N[C@H]2C[C@H](C3=NC4=CC=CC=C4N3)N(C)CC2
Molecular Formula
C21H22N6O
Molecular Weight
374.44
References & Citations
[1]Sadarangani A, et al. GLI2 inhibition abrogates human leukemia stem cell dormancy. J Transl Med. 2015 Mar 21;13:98.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Curated Selection
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