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Glasdegib (Standard)

Glasdegib (Standard) is the analytical standard of Glasdegib. This product is intended for research and analytical applications. Glasdegib (PF-04449913) is a potent and orally bioavailable smoothened inhibitor. Glasdegib (PF-04449913) binds to human SMO (amino acids 181-787) with an IC50 of 4 nM[1].

Product Specifications

CAS Number

1095173-27-5

UNSPSC

12352100

Target

Reference Standards; Smo

Related Pathways

Others; Stem Cell/Wnt

Field of Research

Cancer

Smiles

O=C(NC1=CC=C(C#N)C=C1)N[C@H]2C[C@H](C3=NC4=CC=CC=C4N3)N(C)CC2

Molecular Formula

C21H22N6O

Molecular Weight

374.44

References & Citations

[1]Sadarangani A, et al. GLI2 inhibition abrogates human leukemia stem cell dormancy. J Transl Med. 2015 Mar 21;13:98.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

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