Quinotolast
Quinotolast is an orally active antiallergic agent. Quinotolast inhibits histamine release from rat peritoneal cells. Quinotolast inhibits cutaneous cromoglycate in guinea pig model. Quinotolast has inhibitory effect on histamine and peptide leukotrienes release from guinea pig lung fragments and mouse cultured mast cells. Quinotolast can be studied in allergy-related research[1].
Product Specifications
CAS Number
101193-40-2
UNSPSC
12352005
Target
Histamine Receptor
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Smiles
O=C(C1=CC(OC2=CC=CC=C2)=C3C=CC=CN3C1=O)NC4=NN=NN4
Molecular Formula
C17H12N6O3
Molecular Weight
348.32
References & Citations
[1]Kobayashi, K., et al., (1993) . Effects of quinotolast, a new orally active antiallergic drug, on experimental allergic models. Japanese journal of pharmacology, 63 (1), 73-81.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 3
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