BWC0977 (formic)
BWC0977 formic is an antibacterial agent that inhibits bacterial DNA replication via inhibition of DNA gyrase and topoisomerase IV. BWC0977 formic exhibits a minimum inhibitory concentration (MIC90) of 0.03-2 µg/mL against MDR (Multi-Drug Resistant) Gram-negative bacteria[1].
Product Specifications
CAS Number
[3027162-72-4]
UNSPSC
12352005
Target
Bacterial; DNA/RNA Synthesis; Topoisomerase
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Infection
Purity
98.91
Smiles
O=C1N(C)C2=C(CCNC[C@H]3CN(C4=CN=C(OCC(N5)=O)C5=N4)C(O3)=O)C(F)=CC=C2C=C1.OC=O
Molecular Formula
C23H23FN6O7
Molecular Weight
514.46
References & Citations
[1]Shahul Hameed P, et al. BWC0977, a broad-spectrum antibacterial clinical candidate to treat multidrug resistant infections. Clinical Trial Nat Commun. 2024 Sep 18;15 (1) :8202.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Topoisomerase
Available Sizes
Curated Selection
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