(R) -PHA533533
(R) -PHA533533 is an inactive enantiomer (S) -PHA533533 (active enantiomer) (HY-162683) . (S) -PHA533533 is a CDK2 inhibitor with antitumor activity[1].
Product Specifications
CAS Number
[437982-90-6]
UNSPSC
12352005
Target
CDK; Drug Isomer
Related Pathways
Cell Cycle/DNA Damage; Others
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Smiles
C[C@H](C1=CC=C(N2C(CCC2)=O)C=C1)C(NC3=NNC(C4CC4)=C3)=O
Molecular Formula
C19H22N4O2
Molecular Weight
338.40
References & Citations
[1]Vihma H, et al. Ube3a unsilencer for the potential treatment of Angelman syndrome. Nat Commun. 2024 Jul 8;15 (1) :5558.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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