Epicochlioquinone A
Epicochlioquinone A can inhibit rat liver microsomal ACAT with IC50 of 1.7 μM, inhibit plasma lecithin cholesterol acyltransferase (LCAT) with IC50 of 15.8 μM, and inhibit cholesterol absorption in rats by 50% at 75 mg/kg[1].
Product Specifications
CAS Number
147384-57-4
UNSPSC
12352005
Target
Acyltransferase
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Smiles
C[C@@]12[C@]3([H])[C@@](OC4=C(C(C=C(C4=O)[C@H](C)[C@H](OC(C)=O)[C@@H](C)CC)=O)[C@H]3O)(CC[C@@]1([H])O[C@H](CC2)C(C)(O)C)C
Molecular Formula
C30H44O8
Molecular Weight
532.67
References & Citations
[1]T Fujioka, et al. Epi-cochlioquinone A, a novel acyl-CoA : cholesterol acyltransferase inhibitor produced by Stachybotrys bisbyi. J Antibiot (Tokyo) . 1996 May;49 (5) :409-13.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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