(E/Z) -RA-0002034

(E/Z) -RA-0002034 is a Chikungunya virus (CHIKV) nsP2 protease inhibitor with IC50 of 58 nM. RA-0002034 covalently modifies the catalytic cysteine in a site-specific manner.

Product Specifications

CAS Number

[2305572-22-7]

Product Name Alternative

(E/Z) -RA-2034

UNSPSC

12352005

Target

CHIKV; Influenza Virus

Related Pathways

Anti-infection

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

O=C(C1=NNC(C2=C(OCC)C=CC=C2)=C1)NC/C=C/S(=O)(C)=O

Molecular Formula

C16H19N3O4S

Molecular Weight

349.40

References & Citations

[1]Merten EM, et al. Discovery of a cell-active chikungunya virus nsP2 protease inhibitor using a covalent fragment-based screening approach. bioRxiv [Preprint]. 2024 May 23:2024.03.22.586341.