BAY-593 (hydrochloride)
BAY-593 (hydrochloride) is an orally active GGTase-I inhibitor. BAY-593 (hydrochloride) can block YAP1/TAZ signaling in animals and has antitumor activity[1].
Product Specifications
CAS Number
[2413020-57-0]
UNSPSC
12352005
Target
GGTase; YAP
Related Pathways
Metabolic Enzyme/Protease; Stem Cell/Wnt
Field of Research
Cancer
Smiles
O=C(N1CCC2(CCNC[C@@]2([H])C3=CC=CC=C3OC)CC1)[C@@](OC)(C(F)(F)F)C4=CC=CC=C4.Cl
Molecular Formula
C26H32ClF3N2O3
Molecular Weight
512.99
References & Citations
[1]Graham K, et al. Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling. Cell Chem Biol. 2024 Mar 19:S2451-9456 (24) 00087-4.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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