(rac) -TBAJ-5307

(rac) -TBAJ-5307 is the racemate of TBAJ-5307 (HY-161135) . TBAJ-5307 is a broad spectrum anti-non-tuberculous mycobacteria inhibitor that can target the FO-domain of the engine and preventing rotation and proton-translocation[1].

Product Specifications

CAS Number

[2131783-85-0]

UNSPSC

12352005

Target

Bacterial

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Purity

95.0

Solubility

DMSO : 2.5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

BrC1=CC2=C(N=C(OC)C(C(C3=CC=NC(OC)=C3OC)C(O)(C4=CC(OC)=NC(OC)=C4)CCN(C)C)=C2)C=C1

Molecular Formula

C30H35BrN4O6

Molecular Weight

627.53

References & Citations

[1]Ragunathan P, et, al. High efficacy of the F-ATP synthase inhibitor TBAJ-5307 against non-tuberculous mycobacteria in vitro and in vivo. J Biol Chem. 2024 Jan 2:105618.