BAY 74-4113

BAY 74-4113 is a DGAT1 inhibitor (IC50: 72 nM) . BAY 74-4113 can be used in obesity research[1][2].

Product Specifications

CAS Number

[791593-56-1]

UNSPSC

12352005

Target

Acyltransferase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Metabolic Disease

Smiles

FC1=CC=C2C(SC(NC3=C(C=C(C4=CC=C(C=C4)C([C@H]5[C@@H](CCC5)C(O)=O)=O)C=C3)F)=N2)=C1

Molecular Formula

C26H20F2N2O3S

Molecular Weight

478.51

References & Citations

[1]Roger Smith, et al. Preparation and use of aryl alkyl acid derivatives for the treatment of obesity. US7091228B2. Bayer Pharmaceuticals Corp. 2004-05-06.|[2]Kandre S, et al. Synthesis and evaluation of cyclohexane carboxylic acid head group containing isoxazole and thiazole analogs as DGAT1 inhibitors. Eur J Med Chem. 2014 May 22;79:203-15.