Claramine (hydrochloride)

Claramine hydrochloride is a steroid polyamine with blood-brain barrier permeability. Claramine hydrochloride can regulate the properties of lipid membranes and protect cells from various biological toxins, including misfolded protein oligomers and biological protein-based toxins[1].

Product Specifications

UNSPSC

12352211

Target

Phosphatase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer; Infection

Purity

99.14

Solubility

DMSO : 2.2 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

C[C@@]12[C@]3([H])[C@](C[C@H](C1([H])C[C@H](CC2)O)NCCCNCCCCNCCCN)([H])[C@@]4([H])[C@](CC3)([C@@](CC4)([H])[C@H](C)CCCC(C)C)C.Cl

Molecular Formula

C37H73ClN4O

Molecular Weight

625.45

References & Citations

[1]Kreiser RP, et al. A Brain-Permeable Aminosterol Regulates Cell Membranes to Mitigate the Toxicity of Diverse Pore-Forming Agents. ACS Chem Neurosci. 2022 Apr 20;13 (8) :1219-1231.