Claramine (hydrochloride)
Claramine hydrochloride is a steroid polyamine with blood-brain barrier permeability. Claramine hydrochloride can regulate the properties of lipid membranes and protect cells from various biological toxins, including misfolded protein oligomers and biological protein-based toxins[1].
Product Specifications
UNSPSC
12352211
Target
Phosphatase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer; Infection
Purity
99.14
Solubility
DMSO : 2.2 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
C[C@@]12[C@]3([H])[C@](C[C@H](C1([H])C[C@H](CC2)O)NCCCNCCCCNCCCN)([H])[C@@]4([H])[C@](CC3)([C@@](CC4)([H])[C@H](C)CCCC(C)C)C.Cl
Molecular Formula
C37H73ClN4O
Molecular Weight
625.45
References & Citations
[1]Kreiser RP, et al. A Brain-Permeable Aminosterol Regulates Cell Membranes to Mitigate the Toxicity of Diverse Pore-Forming Agents. ACS Chem Neurosci. 2022 Apr 20;13 (8) :1219-1231.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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