TREX1-IN-4
TREX1-IN-4 (Compound 96) is an inhibitor of both TREX1 and TREX2, with an IC50 for TREX1 of less than 0.1 μM, an IC50 for TREX2 of less than 1 μM, and an EC50 for HCT116 cells ranging from 0.1 to 10 μM. TREX1-IN-4 can be used in cancer research[1].
Product Specifications
CAS Number
[2588445-14-9]
UNSPSC
12352005
Target
DNA/RNA Synthesis
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Smiles
CN(C1=NC(C(NC2=CON=C2)=O)=C(C(N1C)=O)O)[C@H](C3=C(C=CC=C3)Cl)C4=CC(C#N)=CC=C4
Molecular Formula
C24H19ClN6O4
Molecular Weight
490.90
References & Citations
[1]Avinash KHANNA et al, Modulators of trex1, 2021-01-28.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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